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KMID : 0370019870010000093
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Chung-Ang Journal of Pharmacal Sciences
1987 Volume.1 No. 0 p.93 ~ p.97
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The Effect of KAMI-SAMOOL-TANG Water Extract on the Reproduction in Rats
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이송득/Lee, Song Deuk
김일혁/Kim, Il Hyuk
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Abstract
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This study was carried out to investigate the effect of Kami samool Tang water extract on the reproduction in female rats. Three groups, treated for 14 days before mating, were administered with 1.56, 3.12 and 4.68 g / kg / day of water extract respectively. The fourth group was administered with 3.12 g / kg / day of water extract and treated for 10days of early pregnancy. Autopsy was performed on day 16 of gestation to note the number of pregnant animals, the number of implantation sites, the number of live fetuses, and the number of corpora lutea. The results obtained are as follows: 1) In pregestation study, no significant change of the number of implantation sites and live fetuses were obtained. But a significant decrease (p<0.05) of the number of implantation sites and live fetuses was occurred in early gestation 2) it is suggested that Kamisamool-Tang has anti-implantation activities in early gestation, but no ovulatory-suppression activities in pregestation.
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KEYWORD
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